In historical aspect the stages of formation, development and improvement of specialized anti-epidemic team activities in Irkutsk Antiplague Research Institute are presented at natural and epidemiological emergency situations. Participation of the team experts in localization and liquidation of epidemic complications associated with cholera, anthrax, plague and other dangerous and natural-focal infectious diseases is described. The role of mobile formations in the international mass measures and the activity for sanitary-and-epidemiologic human well-being implementation in Priamurye flooding zone is reflected.

Experience of the work organization of specialized anti-epidemic teams of Rospotrebnadzor to support sanitary-and-epidemiologic well-being of the population during Summit АPEС-2012 (Vladivostok) and at the emergency situation caused by abnormal high water in the Far East in 2013 is presented. Variants of specialized anti-epidemic team exploitation in full force or as a group of laboratory-epidemiological strengthening with additional on-site staffing from a personnel reserve of Rospotrebnadzor’s Territorial Institutions are offered and approved in practical activities depending on tasks put to the specialized formation.

The largest natural emergency situations in the history of modern Russia happened in the Siberian and Far Eastern Federal districts. Acceptance of extraordinary measures for realization of sanitary-and-epidemiologic well-being for the suffered population was required. In the article the substantiation of tactical working methods for the specialized anti-epidemic teams (SAET) during various emergency situations is described. It is shown that tactics of SAET reserve group involvement is the most reasonable in the Siberian and the Far Eastern conditions. In this connection it is necessary to provide constant readiness of the reserved SAET with possibility of its deployment in any territory of the region.

The epizootological-epidemiological characteristic of Sochi City as a region of carrying out of the XXII Olympic winter games and the XI Para-olympic winter games in 2014 is presented. A number of actions directed to stabilization of epidemiological conditions concerning the infectious diseases that are dangerous to humans at the period of the Olympic games is described.

The basic principles of diagnostic study organization in mobile laboratories during mass events have been proposed on the model of SAET MC during preparation and conduction of ХХVII World Summer Student Games (Universiade) in 2013 in Kazan and «Group of Twenty» Summit in 2013 in St.Petersburg.

Experience of a group for reception, registration, coding of samples and presentation of the results (RRCG) of the investigations during an operative departure of a specialized anti-epidemic team (SAET) in a high water area in the Amur region in 2013 is described. The algorithm of RRCG work of a mobile SAET complex on the basis of pneumoframe systems is developed.

Being guided by principles of a sanitary anti-epidemic team (SAET) functioning notably mobility, autonomy and also necessity of power resource economy at work in the emergency situation area, it is offered to complete the equipment of SAET laboratories on the basis of pneumoframe modules and the autochassis in addition to the base list of facilities by microwave installations for decontamination of class B wastes.

Workers of several Rospotrebnadzor’s Institutions jointly with a domestic light industry enterprise are developing clothes for protection of employees of a specialized anti-epidemic team from dangerous arthropod (Ixodes and Gamasoidea ticks, fleas, mosquitoes, midges, horseflies and insects) attacks. The given clothes is necessary for epizootological inspection of territories dangerous concerning the transmissible infections and represents a cotton fabric coveralls that must be treated with a special insect-acaricide water emulsion before application.

Problems and the basic directions of the off-nominal specialized formation activities of the Center of Hygiene and Epidemiology in the Novosibirsk region of Rospotrebnadzor are described.

Organization and realization of sanitary-preventive and anti-epidemic actions directed to prevention of mass infectious disease occurrences at elimination of the large-scale flood consequences in 2013 are presented.

Data of the organization and realization of sanitary-preventive and anti-epidemic actions for prevention of mass infectious disease occurrences during preparation to a forthcoming high water in the spring of 2014 are presented.

From the beginning of August to the end of September 2013 there was an unprecedented flooding on the scales in three areas of the Far Eastern Federal district - Khabarovsk Territory, Amur and Jewish Autonomous regions. The high water occurred in Khabarovsk Territory in August 5, 2013, the flooding peak was at the end of August - in the beginning of September, 2013, and the period of a high water lasted till the end of October. As a result of flooding, nine municipal unions have suffered. From the first days of the emergency situation occurrence connected with a high water, Rospotrebnadzor’s Institutions of the Khabarovsk Territory realized a complex of sanitary-antiepidemic and preventive actions directed to the prevention of mass infectious disease occurrences among aggrieved persons and implementation of sanitary-and-epidemiologic human well-being at the Territory. As a result of timely accepted measures it was possible to warn occurrence of acute enteric virus and bacterial infection outbreaks, natural-focal infections, other infectious diseases. The performed measures promoted the decrease of social intensity in the population suffered from flooding.

Organization of the epidemiological situation control in a dangerous biological unit during operation with pathogenic biological agents of I-IV groups is examined. Various approaches to a choice of necessary actions for monitoring of an epidemiological situation and implementation of measures for development and adoption of the relevant administrative decisions are defined.

In article the complex of the measures directed to increase of readiness of the Services and Departments participating in guaranteeing of human protection from threat of importation and distribution of dangerous infectious diseases in the Irkutsk region, import and realization of the hazardous goods, chemical, biological and radioactive substances, wastes and other cargoes capable to cause sanitary-epidemiologic emergency situations is presented.

Infectious diseases associated with epidemiological emergency situations cause a considerable economic damage. By one case of human plague and cholera diseases were analyzed to count the financial expenses for realization of anti-epidemic actions, treatment and other measures in Republic Kazakhstan.

Experience on the organization and realization of disinfection actions in the conditions of an emergency situation caused by large-scale flooding and in after flood period is presented.

The results of the performed measures in the flooding zone, Mikhailovsk and Arkhara areas of the Amur region, are represented. A complex of epidemiological activities conducted in the affected areas prevented worsening of the epidemiological situation and excluded group morbidity in these circumstances.

Directions of activities to support the sanitary-and-epidemiologic human well-being in the conditions of large-scale flooding are described.

The basic organizational and practical anti-epidemic measures for prevention of occurrence and distribution of acute enteric infection outbreaks during high water in 2013 and after the flood period in 2014 are reviewed.

Experience of the organization and vaccination implementation in the population of the Amur region according to epidemic indications in the conditions of an emergency situation caused by large-scale flooding in 2013 and in liquidation of the flooding consequences in 2014 is presented.

The specific prevention of pneumococcal infection (the main cause of influenza and some other acute viral respiratory infection complications) was based on possible reduced rate of natural resistance of human body and increased susceptibility to infectious agents in population suffered from flood in the Far East of Russia in 2013. To provide immunization against pneumococcal infection the elaboration of appropriate protocol of clinical and epidemiological effectiveness against pneumococcal infection was necessary. Implementation of the elaborated standard could guarantee the observance of human rights of enrolled people based on the Declaration of Helsinki World Medical Association, and statistical significance would be reliable.

Results of long-term analysis of sanitary-epidemiological measures aimed to prevent the biological and social emergency occurrences in the Sakha Republic (Yakutia) are represented in the article.

Main results of the Reference center activities for monitoring of the brucellosis agent organized on the basis of Stavropol Plague Control Research Institute in 2008 are presented. A list of information and guidance documents and diagnostic products developed by the experts of the Center is described.

Analysis of shigellosis incidence in the Russian Federation in 2012-2013 is represented. Despite in whole relative epidemiological well-being in the Russian Federation, in some territories shigellosis sickness rate is high enough that requires temporal and spatial studying of regional features of the epidemic process development. Influence of immunization against Sonne dysentery on human morbidity in areas suffered from flooding in 2012 and 2013 is analyzed.

Morbidity of hepatitis C virus (HCV)-infection, HCV genotypes, epidemic situation features in Asia in consideration of climate-geographic, racial and economic characteristics of the territories were analyzed on the basis of E-library, PubMed and Scopus databases including 254 original manuscripts. Hepatitis C has a major economic burden in Asian countries with low gross domestic product.

Frequency of specific antibody detection was 20,2±4,0 % in women with obstetric-gynecologic pathology. Listeria DNA was found in organs of 30,6 % dead born children, 14 cultures of Listeriа monocytogenes serogroup II serovariant 4 were isolated. The data confirmed the etiological role of L. monocytogenes in perinatal pathologies in Khabarovsk city.

A comparative analysis of nasopharyngeal microflora in 320 children of risk groups (frequently ill) and children from organized collectives examined in 2013 (before flood) and in 2014 (after high water) was performed. We revealed a tendency toward increased level of the main bacterial pathogen detections in frequently ill children exposed to stress. Children from organized collectives had a higher level of pneumococcal carriage.

As a rule, exacerbations of an epidemiological situation for brucellosis in the Siberian Federal district are associated with importation of sick animals to its territory and disorder of requirements of the sanitary and veterinary rules for its keeping and realization of preventive actions. Explanation of preconditions and precursors of the epidemiological situation exacerbation for brucellosis is described.

Emergency situations of epidemic type associated with anthrax manifestation were recorded in Siberia and at the Far East in 2004-2013. Total 88 agricultural animals and 25 humans were registered as sick ones. Outbreaks were caused by the pasturing of non-vaccinated livestock in territories of stationary unfavourable anthrax points, compelled slaughter, selling of meat and meat products without veterinary inspection. In 2013 conditions for epizootic and epidemiological anthrax displays were generated during a high water at the Amur River.

Worldwide, anthrax disease is commonly spread among agricultural animals in the developing countries and it is rare in the developed countries. Bacillus anthracis is one of the main causative agents that can be used for bioterrorism purposes. Bacillus anthracis has received enormous attention as means of biological terror in the United States in 2001. In Mongolia, natural anthrax foci were determined in 19 Aimags, Ulanbaatar city and 188 Soums and Districts out of 21 Aimags, city, 340 districts and Soums that were inspected. In the recent years, the number of anthrax cases in humans is increased and the border of the natural foci has been extended to the Gobi region, particularly in the Gobi-Altao, Dundgobi Aimags. An outbreak occurred in Selenge Aimag.

Data of epizootic inspection and epidemiological analysis of anthrax disease in 1950-2013 in Khenthy Aimag of Mongolia are represented. The uniform database including human and animal sickness rate, epizootic foci, stationary unfavourable anthrax points is developed. Features of spatial-temporal dynamics of the morbidity are revealed, the map of ecological-epidemiological division into districts of the Aimag was composed on the basis of climatic zones and the epizootic potential.

To estimate the cholera situation in the Khabarovsk Territory the results of microbiological monitoring of the environments were analyzed at the pre-flood and flooding periods of 2013 for Vibrio cholerae presence. It was shown that along with detection of V. cholerae non-О1/О139 in surface water reservoirs during the pre-flood period, two potentially epidemically dangerous strains containing the determinants of toxin-coregulated pili of adhesion (tcpA) in the genome were isolated from water samples of the Chernaya River. In view of the epidemiological inspection data and single isolation of ctxAB^- tcpA⁺ V. cholerae strains, the probability of its importation to the water reservoir in Khabarovsk city was concluded. The complex of preventive and anti-epidemic actions conducted in the territory after detection of potentially epidemically dangerous V. cholerae eltor strains is described.

Every year monitoring of the environment objects for vibrio flora, the analysis of the monitoring results for Vibrio cholerae, an estimation of readiness for activities in the foci of dangerous infectious diseases including cholera is carried out in Primorye Territory.

Results of vibrioflora monitoring and sanitary-hygienic state of the surface water reservoirs in Priamurie in 2011-2013 were analyzed and also Vibrio cholerae eltor detection at the given territory during the seventh pandemic was retrospectively estimated. It was shown that Vibrio cholerae eltor strains were isolated from surface water reservoirs in the Amur region in 1979, 1981 and 1983 whereas the strain isolation in Khabarovsk Territory lasted throughout the period of supervision with separate pauses. On the basis of the V. cholerae analysis for the last three years the presence of optimum conditions for V. cholerae persistence in some surface water reservoirs of Khabarovsk Territory was concluded. It defines the necessity for enhancement of anti-cholera measures after the high water period.

Probability of importation of infectious diseases dangerous for humans is associated with the peculiarities of air, road and rail traffic. In this paper, transport infrastructure in Zabaikalsky region is considered as an external risk of epidemiological emergency occurrence.

A model that optimizes utilization of resources when preparing to counter the bioterrorism threats or responding to epidemics caused by epidemiologically dangerous or socially significant pathogens is presented. The model is available at http://vector-epimod.ru.

According to the plan realization for maintenance of without poliomyelitis status in the Irkutsk region, the special importance has the actions for timely detection of "wild" poliovirus importation and operative implementation of a complex anti-epidemic measures. In 2009 a case of the poliomyelitis caused by "wild" poliovirus was registered in the nine-month child arrived from Republic Tajikistan to Irkutsk region. The complex of measures permitted to localize the poliomyelitis focus and to prevent distribution of the causative agent in the Irkutsk region population.