A laboratory diagnostic of registered cases of acute respiratory virus infections during autumn-winter-spring periods was performed. A comparative analysis of data of two epidemiological seasons (2013-2014 and 2014-2015) from September through April was done. Annual regular dynamic changes of occurrence of acute respiratory infections were revealed. It was shown that predominant viral pathogen during all seasons was rhinovirus. It was found that during influenza outbreaks there was decreased circulation of other etiological agents of acute respiratory virus infections except respiratory syncytial virus. A comparative analysis of the results of diagnostics among different age groups; young children had higher infection rate and high prevalence of mixed infection.

A comparative analysis of epidemiological and etiological features of two recent outbreaks of influenza in Khabarovsk was performed. Based on the data of epidemiologic surveillance, it was shown that an outbreak detected in 2015 was more severe than an outbreak detected in 2014.The main factor influencing increased morbidity rate and increased rate of severe cases of the disease, was circulation of drift viruses of influenza A(H3N2). The vaccination that did not match with viral etiological agent could not significantly influence on the control of epidemiological process

After 10 years of absence a new outbreak of epidemic parotitis that affected 366 military men of the Far Eastern Military District was registered in 2013.This article focused on epidemiologic investigation of aforementioned outbreak. Some epidemiologic and clinical laboratory features of this outbreak were revealed based on the analysis of 111 medical report

This article describes previously unknown disease, caused by virus of Phlebovirus genus of the family Bunyaviridae among farmers in 2009-2010. A clinical presentation of this viral infection was described in the current article. The viral replication was associated with immunological response and clinical outcome of the infected patients

Based on the results of long-term epidemiological observations, several features of manifestation of natural foci infections, transmitted by ticks are described in this article

Retrospective epizootological-epidemiological analysis of zoogenous infections including anthrax was performed in Sosnov Bor settlement of Zeis к area in Amur region. Data for planning of complex low-rise buildings in Sosnov Bor settlement were studied. Soil samples and fragments of bird bones in Bekkari hole were examined for Bacillus anthracis presence and its DNA. Physical-chemical (acidity, temperature of soils) and biocenotic (nutritional properties and toxicity) features of the soil were studied to reveal the conditions promoting B. anthracis preservation. Biological danger degree of the animal refuse was estimated. Reduction of the sanitary-protective zone extent was established. Actions for rational land-utilization were recommended.

The implementation of complex of anti-epidemic and preventive measures, during the flood of 2013, led to stable epidemiologic situation on the affected territories. A large-scale vaccination against acute intestinal infections (viral hepatitis A, typhoid fever, Sonne dysentery) and influenza was performed. For the first time a specific prevention of pneumococcal infection using vaccine “Prevnar 13” was performed on the territory of Khabarovsk Region among risk group. An evaluation of clinical-epidemiological effectiveness was fulfilled

An microbiological investigation of periodontal pockets in 432 patients with different severity of periodontitis was performed. Bacterium of the genus Leptotrichia, Streptococcus anginosus, Streptococcus viridans, Streptococcus pyogenes group A, Staphylococcus aureus, Escherichia coli, Enterococcus faecalis and other microorganisms were identified. The role of bacterium of the genus Leptotrichia and their associations with other microorganisms during the development periodontitis was analyzed. It was found that the associations of bacterium of the genus Leptotrichia with Streptococcus pyogenes and Staphylococcus aureus were correlated with the severity of clinical symptoms

This article reported the results based on long-term investigations of epidemiologic important pathogens of bacterial hemorrhagic septicemia in fish

Regardless of the content of heavy metals, including mercury, in the water of Amur River, drinking water of municipal water-supply, urban soil and long-term gold mining wastes, there are typical rod-shaped cells, elementary bodies, their aggregates and subsidiary species of unidentified bacteria converted into L-forms, detected by electron microscopy. All of these described forms exists in planktonic and biofilm states, which impedes their detection and identification by routine bacteriological methods. In contrast to the cyst-like resting uncultured cells, some forms of bacteria divide (multiply) into elementary bodies directly in the water, soil and gold mining wastes.

Penicillium canescens, Penicillium chrysogenum, and Penicillium citreo-viride which were initially enriched with Au, Ag, Cu, Ni, Co, Cr, Zn, Pb, Cd, less frequently with Rb, Sr and Cs, have been isolated from long-term gold mining wastes. The level of trace elements increased tens and hundreds of times by culturing the strains in the presence of waste samples. In vitro experiments showed that Penicillium was capable to accumulate elements in the mycelium as well as on the surface of conidia as organo-mineral adsorbate. This happens directly in gold mining wastes. It has been assumed that an excess of heavy metals is one of the causes of fungal aggressive. Sensitization to fungi and metals may increase the rate of occupational allergic diseases.

This review aimed to summarize the modern conceptions regarding epidemiological manifestations of acute water-borne intestinal infections, such as bacterial dysentery, typhoid fever, cholera, rotaviral infection, viral hepatitis A and enteroviral infections. All these infections were characterized by common features, such as high contagiousness in the presence of etiological agent, predominant affection of children, presence of latent component in epidemiological process leading to preservation of causative agent, epidemiological well-being dependence on quality of water supply water disposal, probability of transboundary spreading of infection with subsequent development of outbreak. The significance of acute water-borne intestinal infections in the development of infectious outbreaks significantly increases during liquidation of emergencies, when the risk of infection of affected population is significantly high.

This article elucidated several aspects of intestinal dysbacteriosis as clinical-laboratory syndrome. The most frequent tactical mistakes during diagnostic and treatment of intestinal dysbacteriosis were described. The main trends in the correction of microflora were shown.

This article describes a case of acute vascular failure caused by Lyme borreliosis, which was detected during long-term diagnostic procedures. The outcome of the disease was unfavorable (taking into consideration young patient age, 20 years old) that led to patient disability and discharge from the service.

The data of authors’ own observations regarding clinical and laboratory efficiency of immunoglobulin ("Gabriglobin") for intravenous administration in children with viral meningitis are presented in the current study. Treatment effectiveness was evaluated based on severity and duration of intoxication, cerebral symptoms, meningeal syndrome and changes in cerebrospinal fluid. Inclusion of intravenous immunoglobulin in the complex therapy promoted fast feedback dynamics of clinical syndromes and reduces hospitalization time of an intervention group compared to a control group. Electroencephalographic (EEG) studies helped to identify correspondence of syndrome of liquorodynamic abnormalities of polyrhythmic type of EEG to cerebral and vegetative dystonia syndromes (hypersynchronous type of EEG). Parameters of EEG abnormalities could be used to evaluate the effectiveness of treatment and rehabilitation measures during the recovery period.

A case of generalized Kaposi sarcoma in HIV-infected patient in early stage of the disease is described in this article. Reformed antiretroviral therapy led to tumor regression and improvement of quality of life.