Special nature of enterovirus infection in the Far Eastern and Siberian Federal districts. Molecular-genetic peculiarities of relevant enterovirus types
Abstract
Epidemiological and molecular-genetic analysis of enterovirus infection was conducted in constituent entities of the Far Eastern and Siberian Federal Districts (FEFD and SFD) during years 2016-2019. Challenging epidemic situation concerning specified disease conditioned among other things by disease clusters was revealed in the Altai and Sakha (Yakutia) Republics, Amur, Sakhalin and Irkutsk regions. In addition, a substantial increase in cases of meningitis caused by enterovirus was detected in the Krasnoyarsk krai, Tuva and Sakha (Yakutia) Republics during the analyzed period of time. Results of molecular-genetic research evidence that substantial increase in incidence during years 2017-2019 were caused mostly by Coxsackie A-6.
About the Authors
E. Yu. Sapega
FBIS Khabarovsk scientific research institute of epidemiology and microbiology of Rospotrebnadzor (Federal service for surveillance on consumers rights protection and human wellbeing)
Russian Federation
Russian Federation
Khabarovsk
L. V. Butakova
FBIS Khabarovsk scientific research institute of epidemiology and microbiology of Rospotrebnadzor (Federal service for surveillance on consumers rights protection and human wellbeing)
Russian Federation
Russian Federation
Khabarovsk
O. E. Trotsenko
FBIS Khabarovsk scientific research institute of epidemiology and microbiology of Rospotrebnadzor (Federal service for surveillance on consumers rights protection and human wellbeing)
Russian Federation
Russian Federation
Khabarovsk
T. A. Zaitseva
Regional Rospotrebnadzor office in the Khabarovsk krai
Russian Federation
Russian Federation
FBIS Khabarovsk scientific research institute of epidemiology and microbiology of Rospotrebnadzor (Federal service for surveillance on consumers rights protection and human wellbeing)
O. P. Kurganova
Regional Rospotrebnadzor office in the Amur oblast
Russian Federation
Russian Federation
Blagoveshchensk
M. E. Ignatyeva
Regional Rospotrebnadzor office in the Republic Sakha (Yakutiya)
Russian Federation
Russian Federation
Yakutsk
O. A. Funtusova
Regional Rospotrebnadzor office in the Sakhalin oblast
Russian Federation
Russian Federation
Yuzhno-Sakhalinsk
P. V. Kopilov
Regional Rospotrebnadzor office in the Jewish Autonomous region
Russian Federation
Russian Federation
Birobidzhan
A. V. Semenikhin
Regional Rospotrebnadzor office in the Chukotka autonomous region
Russian Federation
Russian Federation
Anadyr
T. N. Detkovskaya
Regional Rospotrebnadzor office in the Primorsky region
Russian Federation
Russian Federation
Vladivostok
Ya. N. Gospodarik
Regional Rospotrebnadzor office in the Kamchatka krai
Russian Federation
Russian Federation
Petropavlovsk-Kamchatsky
S. A. Korsunskaya
Regional Rospotrebnadzor office in the Magadan oblast
Russian Federation
Russian Federation
Magadan
S. E. Lapa
Regional Rospotrebnadzor office in the Zabailalsky krai
Russian Federation
Russian Federation
Chita
D. F. Savinikh
Regional Rospotrebnadzor office in the Irkutsk oblast
Russian Federation
Russian Federation
Irkutsk
S. S. Khankhareev
Regional Rospotrebnadzor office in the Republic Buryatia
Russian Federation
Russian Federation
Ulan-Ude
T. G. Romanova
Regional Rospotrebnadzor office in the Republic Khakassia
Russian Federation
Russian Federation
Abakan
D. V. Goryaev
Regional Rospotrebnadzor office in the Krasnoyarsk krai
Russian Federation
Russian Federation
Krasnoyarsk
L. V. Shuchinov
Regional Rospotrebnadzor office in the Altai Republic
Russian Federation
Russian Federation
Gorno-Altaisk
L. K. Salchak
Regional Rospotrebnadzor office in the Tyva Republic
Russian Federation
Russian Federation
Kyzyl
References
1. Бессмертный Б.С., Ткачева М.Н. Статистические методы в эпидемиологии. – М.:Медгиз, 1961. – 106 с.
2. Демина А.В., Маркович Н.А., Нетесов С.В. Энтеровирусы. Часть 1: история открытия, таксономия, строение генома, эпидемиология Бюллетень СО РАМН, № 1 (129), 2008 г.
3. Савилов Е.Д., Астафьев В.А., Жданова С.Н., Заруднев Е.А. Эпидемиологический анализ: Методы статистической обработки материала. – Новосибирск: Наука-Центр, 2011. – 156 с.
4. Скачков М.В., Альмишева А.Ш., Плотников А.О., Немцева Н.В., Верещагин Н.Н., Скворцов В.О. Эпидемиологические и экологические аспекты энтеровирусной инфекции// Эпидемиология и вакцинопрофилактика- 2008. №6. -С. 29-35.
5. Drummond A.J., Suchard M.A., Xie D., et al. Bayesian phylogenetics with BEAUTi and the BEAST 1.7. // Molecular Biology and Evolution. 2012. Vol. 29, N8. P. 1969-1973.
6. Nix W.A, Oberste M.S, Pallansch M.A. Sensitive, seminested PCR amplification of VP1 sequences for direct identification of all enterovirus serotypes from original clinical specimens // Journal of Clinical Microbiology. 2006. Vol. 44, N8. P. 2698-2704.
7. Shapiro B., Rambaut A., Drummond A.J. Choosing appropriate substitution models for the phylogenetic analysis of protein-coding sequences // Molecular Biology and Evolution. 2006. Vol. 23, N1. P. 7-9.
Review
For citations:
Sapega E.Yu., Butakova L.V., Trotsenko O.E., Zaitseva T.A., Kurganova O.P., Ignatyeva M.E., Funtusova O.A., Kopilov P.V., Semenikhin A.V., Detkovskaya T.N., Gospodarik Ya.N., Korsunskaya S.A., Lapa S.E., Savinikh D.F., Khankhareev S.S., Romanova T.G., Goryaev D.V., Shuchinov L.V., Salchak L.K. Special nature of enterovirus infection in the Far Eastern and Siberian Federal districts. Molecular-genetic peculiarities of relevant enterovirus types. Far Eastern Journal of Infectious Pathology. 2020;(39):50-59. (In Russ.)
Views:
11
Email this article 