OSMOTIC DEMYELINATING SYNDROME IN THE PRACTICE OF DOCTORS OF VARIOUS SPECIATIES
https://doi.org/10.62963/2073-2899-2024-46-76-80
Abstract
A clinical case of a rare, severe and difficult to diagnose iatrogenic lesion of the central nervous system - osmotic demyelinating syndrome (ODS) and a brief review of the literature is presented. Osmotic demyelinating syndrome with damage to the pons of the brain developed in a 36-year-old woman, HIV-infected, suffering from alcoholism with polyvisceropathy, drug addiction, chronic hepatitis of high activity and chronic pancreatitis in the acute stage. The condition was accompanied by moderate hyponatremia. This clinical observation will be of interest to doctors of various specialties, will expand the understanding of the clinical manifestations and treatment of ODS and will allow for the prevention or timely diagnosis of such a rare pathology.
About the Authors
T. A. Zakharycheva
FSBEI HE Far Eastern State Medical University of the Ministry of Health of the Russian Federation; RSBHI Regional Clinical Hospital named after professor O.V. Vladimirtsev of the Ministry of Health of the Khabarovsk Region
Russian Federation
Russian Federation
Khabarovsk
A. S. Shirokova
Postgraduate Institute for Public Health Workers of the Ministry of Health of the Khabarovsk Region
Russian Federation
Russian Federation
Khabarovsk
S. А.k. Аzimova
FSBEI HE Far Eastern State Medical University of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Khabarovsk
A. G. Polyakov
RSBHI Regional Clinical Hospital named after professor O.V. Vladimirtsev of the Ministry of Health of the Khabarovsk Region
Russian Federation
Russian Federation
Khabarovsk
P. P. Senchikov
RSBHI Regional Clinical Hospital named after professor O.V. Vladimirtsev of the Ministry of Health of the Khabarovsk Region
Russian Federation
Russian Federation
Khabarovsk
References
1. Семенов В.А., Захарычева Т.А., Зуева С.А. и др. Осмотический демиелинизирующий синдром и его проявления. Вестник неврологии, психиатрии и нейрохирургии. 2024; 1(168):73-82. doi: 10.33920/med-01-2401-07.
2. Трофимова Т.Н., Сафронов Г.А., Беляков Н.А., Медведев С.В. Лучевая диагностика токсических поражений головного мозга. Лучевая диагностика и терапия. 2011;1(2):37-46.
3. Шевелева ЕМ, Заславский ЛГ, Ковеленов АГ и др. Центральный понтинный и экстрапонтинный миелинолиз: обзор литературы и собственное наблюдение. Ученые записки Санкт-Петербургского государственного медицинского университета им. академика И.П. Павлова. 2020;27(2):72-8. doi: 10.24884/1607-4181-2020-27-2-72-78.
4. Adams RD, Victor M, Mancall EL. Central pontine myelinolysis. A hitherto undescribed disease occurring in alcoholic and malnourished patients. AMA Arch Neurol Psychiatry. 1959;81(2):154-172.
5. Alleman AM. Osmotic demyelination syndrome: Central pontine myelinolysis and extrapontine myelinolysis. Seminars in Ultrasound, CT and MRI. 2014;35(2):153-159. doi: 10.1053/j.sult.2013.09.009.
6. Graff-Radford J, Fugate JE, Kaufmann TJ, Mandrekar JN, Rabinstein AA. Clinical and radiologic correlations of central pontine myelinolysis syndrome. Mayo Clinic proceedings. 2011;86(11):1063-1067. doi: 10.4065/mcp.2011.0239.
7. Hsieh CY, Huang CW. Extrapontine myelinolysis in a patient following correction of hyponatremia. Acta Neurol Taiwan. 2007 Sep;16(3):188-9. PMID: 17966961.
8. Kleinschmidt-Demasters BK, Rojiani AM, Filley CM. Central and extrapontine myelinolysis: then ... and now. Journal of neuropathology and experimental neurology. 2006;65(1):1-11. doi: 10.1097/01.jnen.0000196131.72302.68.
9. Lambeck J, Hieber M, Dressing A, et al. Central Pontine Myelinosis and Osmotic Demyelination Syndrome. Dtsch Arztebl Int. 2019 Sep 2;116(35-36):600-6. doi: 10.3238/arztebl.2019.0600.
10. Ruiz-Sandoval JL, Chiquete E, Alvarez-Palazuelos LE at al. Atypical forms of the osmotic demyelination syndrome. Acta Neurologica Belgica. 2013;113(1):19-23. doi: 10.1007/s13760-012-0110-5
11. Stakhovskaya LV, Erokhina LG, Leskova NN, Gubsky LV. Central pontine and extrapontine myelinolysis. Journal of Neurology and Psychiatry. 2000;100(2):55-58.
Review
For citations:
Zakharycheva T.A., Shirokova A.S., Аzimova S.А., Polyakov A.G., Senchikov P.P. OSMOTIC DEMYELINATING SYNDROME IN THE PRACTICE OF DOCTORS OF VARIOUS SPECIATIES. Far Eastern Journal of Infectious Pathology. 2024;(46):76-80. (In Russ.) https://doi.org/10.62963/2073-2899-2024-46-76-80
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