PECULIARITIES OF GENOTYPE DISTRIBUTION OF HIV-1 AND HEPATITIS C VIRUS AMONG PATIENTS WITH HIV AND CHRONIC HEPATITIS C CO-INFECTION IN CONSTITUENT ENTITIES OF THE FAR EASTERN FEDERAL DISTRICT
https://doi.org/10.62963/2073-2899-2024-46-45-49
Abstract
A comparative analysis of HIV-1 and hepatitis C virus (HCV) among patients with monoinfection as well a co-infection residing in constituent entities of the Far Eastern Federal district. It was established that HIV-1 sub-subtype A1 (84.7%) was detected more frequently among people living with HIV (PLWH) compared to individuals co-infected with HIV-1 and HCV (62.8%). Among the latter, prevalence of HIV-1 recombinant forms was 2.7 times higher (32.6%) compared to HIV monoinfected people (11.9%). HCV subtype 3a was identified more frequently among patients co-infected with HIV-1 and HCV (49.1%). HCV 1b (40.6%), 2 (5.7%) and 1a (4.7%) genovariants were less common. However, in general, there were practically no differences in the distribution of HCV genotypes be- tween examined groups. In addition to evaluating general patterns of pathogens genetic variants circulation, it is advisable to estimate peculiarities of their distribution depending on gender and presence of co-infection.
About the Authors
E. A. BazykinaRussian Federation
Khabarovsk
V. O. Kotova
Russian Federation
Khabarovsk
O. E. Trotsenko
Russian Federation
Khabarovsk
L. A. Balakhontseva
Russian Federation
Khabarovsk
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Review
For citations:
Bazykina E.A., Kotova V.O., Trotsenko O.E., Balakhontseva L.A. PECULIARITIES OF GENOTYPE DISTRIBUTION OF HIV-1 AND HEPATITIS C VIRUS AMONG PATIENTS WITH HIV AND CHRONIC HEPATITIS C CO-INFECTION IN CONSTITUENT ENTITIES OF THE FAR EASTERN FEDERAL DISTRICT. Far Eastern Journal of Infectious Pathology. 2024;(46):45-49. (In Russ.) https://doi.org/10.62963/2073-2899-2024-46-45-49