SELENIUM AND FREE RADICAL OXIDATION IN PATIENTS SUFFERING FROM HEMORRHAGIC FEAVER WITH RENAL SYNDROME
Abstract
Twenty-three patients with median age of 37,4±4,05 suffering from hemorrhagic fever with renal syndrome (HFRS) were studied. All patients were examined for the levels of selenium in the blood serum and free radical oxidation (FRO) indices with the biochemicoluminescence method. The tests revealed that during the period of early apyrexia in patients with HFRS was registered significant decrease of selenium level in blood serum as compared to the period of late convalescence and control group. At the same time, there were no significant difference between selenium concentration during the period of late convalescence and in the control group. The research revealed significant moderate inverse correlation between the level of selenium in blood serum and FRO indices. This finding reflects intensity of the process of free radical oxidation in the blood serum.
About the Authors
A. . Yu Martinenko
State-Financed Educational Institution of the Higher Professional Education «Far Eastern State Medical University»
Russian Federation
Russian Federation
Yu. G. Kovalskiy
State-Financed Educational Institution of the Higher Professional Education «Far Eastern State Medical University»
Russian Federation
Russian Federation
G. S. Tomilka
State-Financed Educational Institution of the Higher Professional Education «Far Eastern State Medical University»
Russian Federation
Russian Federation
O. A. Lebedko
State-Financed Educational Institution of the Higher Professional Education «Far Eastern State Medical University»
Russian Federation
Russian Federation
N. A. Golubkina
Federal State Funded Research Institution All-Russian Institute for Selection and Seed-Breeding of Vegetables
Russian Federation
Russian Federation
E. G. Ryabtseva
State-Financed Educational Institution of the Higher Professional Education «Far Eastern State Medical University»
Russian Federation
Russian Federation
T. V. Mzhelskaya
Federal State Institution of Science State Khabarovsk research institute of epidemiology and microbiology of Federal service for surveillance on customer rights protection and human wellbeing (Rospotrebnadzor)
Russian Federation
Russian Federation
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Review
For citations:
Yu Martinenko A., Kovalskiy Yu.G., Tomilka G.S., Lebedko O.A., Golubkina N.A., Ryabtseva E.G., Mzhelskaya T.V. SELENIUM AND FREE RADICAL OXIDATION IN PATIENTS SUFFERING FROM HEMORRHAGIC FEAVER WITH RENAL SYNDROME. Far Eastern Journal of Infectious Pathology. 2016;(31):64-67. (In Russ.)
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