STUDY OF FRANCISELLA TULARENSIS NIIEG-15 VACCINE STRAIN STABILITY AFTER DIFFERENT STORAGE PERIODS
Abstract
Variability of cultural, morphological, biochemical, genetic and immunobiological properties of Francisella tularensis 15 NIIEG strains dried in 1953, 1966, 1969, 1987, 1990 , 2003 and 2012 and stored in a National collection of pathogenic bacteria (Russia) was detected. These data confirmed the need for a continuing study to maintain the stability of the F. tularensis 15 NIIEG strain.
About the Authors
E. A. Solovyev
Scientific Center on expertise of medical application products of Ministry of Health of Russian Federation, Moscow
Russian Federation
Russian Federation
L. V. Sayapina
Scientific Center on expertise of medical application products of Ministry of Health of Russian Federation, Moscow
Russian Federation
Russian Federation
A. A. Goryaev
Scientific Center on expertise of medical application products of Ministry of Health of Russian Federation, Moscow
Russian Federation
Russian Federation
N. A. Osina
Russian Research Anti-Plague Institute «Microbe», Saratov
Russian Federation
Russian Federation
M. P. Rudnik
Scientific Center on expertise of medical application products of Ministry of Health of Russian Federation, Moscow
Russian Federation
Russian Federation
D. S. Davydov
Scientific Center on expertise of medical application products of Ministry of Health of Russian Federation, Moscow
Russian Federation
Russian Federation
V. P. Bondarev
Scientific Center on expertise of medical application products of Ministry of Health of Russian Federation, Moscow
Russian Federation
Russian Federation
References
1. Мещерякова И.С. Туляремия: современная эпидемиология и вакцинопрофилактика // Эпидемиология и вакцинопрофилактика. - 2010. - № 2 (51). - С. 17-22.
2. Олсуфьев Н.Г., Емельянова О.С., Угловой Г.П.,и др. Сравнительные испытания на людях вариантов вакцинного туляремийного штамма 15 Гайского // Журн. микробиол. и иммунобиол. - 1971. - № 5. - С. 55-57.
3. Профилактика туляремии. Санитарно-эпидемиологические правила. СП 3.1.7.2642-10 // Бюлл. норм. и метод. документов Госсанэпиднадзора. - 2010. - Вып. 3. - С. 15-35.
Review
For citations:
Solovyev E.A., Sayapina L.V., Goryaev A.A., Osina N.A., Rudnik M.P., Davydov D.S., Bondarev V.P. STUDY OF FRANCISELLA TULARENSIS NIIEG-15 VACCINE STRAIN STABILITY AFTER DIFFERENT STORAGE PERIODS. Far Eastern Journal of Infectious Pathology. 2014;(25):109-111. (In Russ.)
Views:
98
Email this article 