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CIRCULATING RECOMBINANT FORMS OF HIV-1 IN CONSTITUENT ENTITIES OF THE FAR EASTERN FEDERAL DISTRICT

Abstract

Molecular-epidemiological analysis showed that despite domination of sub-subtype A6 in the Far Eastern Federal district (FEFD) genetic profile of HIV-infection was diverse. A total number of 91 recombinant forms were found among people living with HIV. Seven types of circulating recombinant forms (CRF) and one unique recombinant form (URF) of HIV-1 were identified: CRF03_AB – 4 (4.4±2.2%), CRF02_AG – 14 (15.6±3.8%), CRF63_02A1 – 65 (71.1±4.8%), CRF11_cpx – 1 (1.1±1.1%), CRF01_AE – 4 (4.4±2.2%), CRF09_cpx 1(1.1±1.1%), CRF07_BC– 1 (1.1±1.1%), URF63_02A– 1 (1.1±1.1%). Moderate abundance of circulating recombinant forms was revealed in Jewish autonomous district and Amur oblast. Cause of an increase of HIV-1 recombinant forms spread in the FEFD can be a result of high internal and external migration.

About the Authors

V. O. Kotova
FBUN Khabarovsk research institute of epidemiology and microbiology of the Federal service for surveillance on consumers rights protection and human wellbeing (Rospotrebnadzor)
Russian Federation


L. A. Balakhontseva
FBUN Khabarovsk research institute of epidemiology and microbiology of the Federal service for surveillance on consumers rights protection and human wellbeing (Rospotrebnadzor)
Russian Federation


E. A. Bazykina
FBUN Khabarovsk research institute of epidemiology and microbiology of the Federal service for surveillance on consumers rights protection and human wellbeing (Rospotrebnadzor)
Russian Federation


O. E. Trotsenko
FBUN Khabarovsk research institute of epidemiology and microbiology of the Federal service for surveillance on consumers rights protection and human wellbeing (Rospotrebnadzor)
Russian Federation


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Review

For citations:


Kotova V.O., Balakhontseva L.A., Bazykina E.A., Trotsenko O.E. CIRCULATING RECOMBINANT FORMS OF HIV-1 IN CONSTITUENT ENTITIES OF THE FAR EASTERN FEDERAL DISTRICT. Far Eastern Journal of Infectious Pathology. 2021;(40):79-87. (In Russ.)

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ISSN 2073-2899 (Print)