infectpataogДальневосточный журнал инфекционной патологииFar Eastern Journal of Infectious Pathology2073-2899ФБУН Хабаровский НИИ эпидемиологии и микробиологии Роспотребнадзораinfectpataog-286Research ArticleВИРУСНЫЕ ИНФЕКЦИИVIRAL INFECTIONSРОТАВИРУСНАЯ ИНФЕКЦИЯ В ХАБАРОВСКОМ КРАЕROTAVIRUS INFECTION IN THE KHABAROVSK KRAIСапегаЕ. Ю.SapegaE. Yu.

Сапега Елена Юрьевна – кандидат медицинских наук, руководитель Дальневосточного регионального научно-методического центра по изучению энтеровирусных инфекций 

 г. Хабаровск 

 Khabarovsk 

evi.khv@mail.ruБутаковаЛ. В.ButakovaL. V.

 г. Хабаровск 

 Khabarovsk 

ТроценкоО. Е.TrotsenkoO. E.

 г. Хабаровск 

 Khabarovsk 

ЗайцеваТ. А.ZaitsevaT. A.

 г. Хабаровск 

 Khabarovsk 

КаравянскаяТ. Н.KaravyanskayaT. N.

 г. Хабаровск 

 Khabarovsk 

ГарбузЮ. А.GarbuzYu. A.

 г. Хабаровск 

 Khabarovsk 

ЛебедеваЛ. А.LebedevaL. A.

 г. Хабаровск 

 Khabarovsk 

ФБУН Хабаровский НИИ эпидемиологии и микробиологии РоспотребнадзораРоссияFBUN Khabarovsk research institute of epidemiology and microbiology of the Federal service for surveillance on consumers rights protection and human wellbeing (Rospotrebnadzor)Russian FederationУправление Роспотребнадзора по Хабаровскому краюРоссияRospotrebnadzor regional office in the Khabarovsk kraiRussian FederationФБУЗ «Центр гигиены и эпидемиологии» в Хабаровском краеРоссияFBUN “Center of hygiene and epidemiology” in the Khabarovsk kraiRussian Federation2023010620250452431Copyright © Сапега Е.Ю., Бутакова Л.В., Троценко О.Е., Зайцева Т.А., Каравянская Т.Н., Гарбуз Ю.А., Лебедева Л.А., 20252025Сапега Е.Ю., Бутакова Л.В., Троценко О.Е., Зайцева Т.А., Каравянская Т.Н., Гарбуз Ю.А., Лебедева Л.А.Sapega E.Y., Butakova L.V., Trotsenko O.E., Zaitseva T.A., Karavyanskaya T.N., Garbuz Y.A., Lebedeva L.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://infectpataog.elpub.ru/jour/article/view/286

Проведён эпидемиологический анализ заболеваемости ротавирусной инфекцией и проанализированы результаты молекулярно-генетического мониторинга ротавирусов, циркулировавших в Хабаровском крае в 2022 г. Установлено, что показатель заболеваемости ротавирусной инфекцией в 2022 г. оказался несколько выше среднемноголетнего уровня, рассчитанного за период 2010–2019 гг. (92,3 и 90,5 на 100 тыс. населения соответственно). Среди заболевших выявлено преобладание детей дошкольного возраста. В 2022 г. в детских образовательных организациях зарегистрировано 4 очага групповой заболеваемости ротавирусной инфекцией. Молекулярно-генетическое исследование возбудителей, обнаруженных в очагах групповой заболеваемости, установило циркуляцию в них трёх широко распространенных по G-генотипу ротавирусов: G9, G4 и G3. Филогенетический анализ ротавирусов А генотипа G9 указал на возможный их завоз из стран Юго-Восточной Азии, а штаммов ротавирусов А генотипа G3 – позволил их отнести к реассортантам. По Pгенотипу штаммы ротавирусов, полученные из очагов групповой заболеваемости в Хабаровском крае, вошли в линию P[8]-3. Регулярный мониторинг за ротавирусами, проводимый на фоне постоянного эпидемиологического анализа заболеваемости, позволяет более полно охарактеризовать эпидемический процесс ротавирусной инфекции на конкретной территории.

Epidemiological analysis of rotavirus infection incidence was carried out and results of molecular genetic monitoring of rotaviruses circulating in the Khabarovsk krai during year 2022 were analyzed. It was established that rotavirus infection incidence rate in the year 2022 was slightly higher than longterm average level calculated for the period of observation that included years 2010–2019 (92.3 and 90.5 per 100 000 population, respectively). Predominance of preschool children was revealed among infected patients. Four outbreaks of rotavirus infection were registered in children's educational institutions in the year 2022. Molecular genetic analysis of pathogens found in foci of the outbreaks revealed circulation of three prevalent G-genotype rotaviruses: G9, G4 and G3. Phylogenetic analysis of rotavirus A genotype G9 indicated their possible importation from the countries of Southeast Asia when analysis of rotavirus A genotype G3 strains allowed to classify them as reassortants. Other rotavirus strains obtained from the foci of the disease outbreaks located the Khabarovsk krai were typed as P[8]-3 lineage in accordance with P-genotype strains. Regular monitoring of rotaviruses carried out against the background of continuous epidemiological analysis of incidence makes it possible describe the epidemic process of rotavirus infection in a specific territory more accurately.

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The authors declare that there are no conflicts of interest present.